Did you know research has shown combining caffeine with other supplements can boost their effectiveness by up to 40%, while also providing a natural burst of energy?
It’s true! That’s exactly why we combined a small amount of this powerful energy-boosting, natural substance with a large dose of a second natural substance – called glucuronolactone – known for its mood-boosting properties.
Below, you’ll discover how these two natural substances, combined together in a supplement called ‘Wide Awake!’, can help every day start with happy, energetic lift in your step!
Here’s what you need to know…
Hi, Steve Barwick here, for Targeted Nutrients…
You probably already know that caffeine is the most widely used “energy substance” in the world. Virtually every culture uses caffeine on a daily basis – either in the form of coffee, tea or cocoa – for its energy-boosting and brain-boosting “alertness” benefits.
But clinical research also demonstrates that when used in moderation, caffeine has some astonishing, lesser-known healing and anti-aging properties, as well as properties that help slow or even prevent the onset of serious degenerative diseases. For example, caffeine:
- Boosts memory – Japanese researchers have found that caffeine consumption in the mornings boosts memory and cognition throughout the day.
- Reduces Memory Loss – Researchers from Johns Hopkins University demonstrated that a daily caffeine pill helped boost “memory consolidation,” which is to say, the ability of the body to convert short-term memory into long-term memory, and to “hold” it in the brain.
- Reduces Risk of Dementia – A study published in the Journals of Gerontology, titled the “Women’s Health Initiative Memory Study,” demonstrated that older women who consumed 261 mg. of caffeine per day or more had a reduced risk of developing dementia or memory impairment.
- Reduces Alzheimer’s Risk – According to researchers from the University of South Florida Alzheimer’s Disease Research Center, back-to-back animal studies demonstrated that caffeine “markedly reduced the hallmark protein for Alzheimer’s disease in the brain and blood” of the test animals that were specially bred to exhibit symptoms of the disease.
- Lowers Risk of Developing Erectile Dysfunction – According to research from the University of Texas Medical School published in the journal PLOS in 2015, men who consume 250 to 375 mg. of caffeine per day have a much lower risk of developing erectile dysfunction than men who don’t. Reduced risk for ED was seen even in men consuming as little as 85 mg. of caffeine per day.
- Protects Blood-Brain Barrier – Research published in the Journal of Neuroinflammation demonstrates that caffeine helps protect the blood-brain barrier from becoming “leaky,” which in turn helps prevent brain damage responsible for Alzheimer’s disease. According to the BBC, the study also found that caffeine “…may cut the risk of dementia by blocking the damage cholesterol can inflict on the body…”
- Reduces Risk of Chronic Inflammation – In a study published in the journal Nature Medicine in January 2017, researchers from Stanford University have discovered that regular caffeine use helps block the expression of a gene responsible for low-grade chronic inflammation as we age. This inflammation is said to be responsible for high blood pressure, hardening of the arteries and heart disease.
- Lowers Risk of Parkinson’s Disease – Research published in the journal Scientific Reports in 2015 demonstrated that those who consume the most caffeine are at less risk for developing Parkinson’s disease, and that this “caffeine effect” proved true even among people who were genetically predisposed to develop Parkinson’s.
- Reduces Risk of Stroke – In a study published in 2011 in the journal Stroke, researchers followed 34,670 women aged 49-83 for over 10 years. Those who drank no caffeinated coffee had a significantly higher risk of stroke than those who drank caffeinated coffee. In fact, risk of stroke was 22-25% less for the consumers of caffeinated coffee than for the non-consumers.
- Reduces Risk of Fatty Liver Disease – A study conducted by researchers at George Mason University demonstrated that caffeine has a positive effect on non-alcoholic fatty liver disease, and that two cups of coffee per day “could help sufferers of liver disease.”
- Improves Lung Function – A 2012 study published in the Cochrane Database of Systematic Reviews demonstrated that in people with asthma, caffeine acted as an effective bronchiodilator, widening airways in the lungs and helping restore breathing and relieving symptoms of asthma. According to the review, the evidence shows that “…even small amounts of caffeine can improve lung function for up to four hours.”
- Reduces Kidney Stone Risk – In research conducted at the Division of Nephrology at the Catholic University of the Sacred Heart in Rome, Italy, researchers found that in a 217,883 person study, people who ingested caffeine from any source had lower risk of kidney stone development than people who did not consume caffeine.
- Reduces Muscle Pain as Well as Aspirin/Ibuprofen – Researchers at the University of Georgia found that moderate doses of caffeine can reduce post-workout muscle pain by up to 48% and appeared to work better than aspirin or ibuprofen, according to researcher Patrick J. O’Connor whose study was published in March 2007 in The Journal of Pain.
- Improves Muscle Energy – According to the Journal of Applied Physiology, caffeine helps the body replenish lost glycogen concentrations faster after exercise, resulting in 66% higher glycogen levels after strenuous exercise than in people who did not take caffeine. (Glycogen is a polysaccharide used by the body to help power muscle activity.)
- Boosts Exercise Performance – 11 different studies have demonstrated that caffeine ingestion yields “significant improvement” in exercise performance, and a related 2014 study published in the Journal of Applied Physiology found that caffeine increased the level of enjoyment from exercise, and caused test subjects to burn more calories and consume less calories after exercise.
- Lowers Risk of Suicide – Research published in the World Journal of Biological Psychiatry in 2014 demonstrated that people with higher caffeine intake had a significantly lower risk of suicide.
- Reduces Risk of Cataracts – Research conducted at the Department of Ophthalmology and Visual Sciences at the University of Maryland School of Medicine demonstrated that caffeine eye drops “greatly reduced” risk of cataract formation in animals given a cataract-inducing drug.
- Reduces Risk of Tinnitus – In a study titled “Caffeine Intake and Risk of Incident of Tinnitus,” published in 2014 in the American Journal of Medicine, researchers who followed 65,085 women, aged 30-44, for 18 years, found that higher caffeine intake was directly associated with a significantly lower risk of development of tinnitus in women.
And believe it or not, there are many, many more studies demonstrating the plethora of positive benefits from regular daily caffeine ingestion. These studies have turned medical science’s previous understanding of caffeine on its head.
And it’s prompted at least one prominent researcher to proclaim, “Caffeine isn’t a drug, it’s a vitamin!”
As clinical researcher Lisa Pawloski, who chairs the Department of Nutrition and Food Studies at George Mason University recently stated:
“I was actually surprised by the caffeine effect…Caffeine is showing benefit for such diseases as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes…It used to be people would say they’re cutting back on caffeine. But there is a change in the attitudes about caffeine consumption…it’s not necessarily a bad thing to include in your diet.”
And as Dr. Jonathan Geiger of the University of North Dakota recently stated:
“Caffeine is safe and readily available and its ability to stabilize the blood-brain barrier means it could have an important part to play in therapies against neurological disorders.”
According to Dr. Michael Greger, M.D., a graduate of Cornell University and author of the best-selling book, How Not to Die:
“Up to a thousand milligrams of caffeine is considered safe for most people, which translates into about 10 cups of coffee a day.”
So caffeine usage is gaining in prominence among clinical researchers who have studied its many promising health benefits and healing qualities. And it turns out we just might have to re-think everything we once thought we knew about caffeine. As Ernest Hemingway once said, “Caffeine puts a man back on his horse.”
Creating the Perfect Natural Morning Pick-Me-Up
Wide Awake! was designed by Targeted Nutrients to be used as a morning energizer in place of coffee, or better still, in place of those unhealthy, sugar-laden, so-called “energy drinks” like Red Bull, Rock Star, 5 Hour Energy or Monster Energy.
We actually experimented with 12 different all-natural ingredients while we were formulating Wide Awake! before finally deciding on using only the following two:
1) A very small amount of high-quality natural anhydrous caffeine (about as much as you’d find in a cup of Starbucks coffee)
2) A nice big dose of glucoronolactone, the energizing and pleasure-inducing all-natural glucose molecule that’s used by some of the world’s top “smart drug” enthusiasts for its ability to increase mental alertness, trigger euphoria and even stimulate healing from toxins.
We added a small amount of caffeine to Wide Awake! because of the astonishing array of brand-new research that’s been coming out on its positive benefits for lifetime health and well-being, as noted above.
And that’s not just “coffee industry” research, either, but research from prestigious universities like Harvard, Stanford, Johns Hopkins, George Mason, and numerous top medical universities as well. Even the American Cancer Association is doing studies on caffeine, and finding remarkable protective benefits.
As you read above, caffeine has many often-overlooked health benefits…but there’s one particular benefit I failed to mention. This benefit is so impressive, it’s what truly cinched the deal for us when we first decided to formulate a morning energizer supplement:
You see, it turns out that for years now drug companies have been adding small amounts of caffeine to prescription drugs, as well as to over-the-counter medicines such as painkillers, cold and flu medications, cough and nasal decongestants and more.
Why have they been adding caffeine to drugs?
It’s because modern science has discovered that adding a small amount of caffeine to medications helps boost the effectiveness and healing properties of those medications by up to 40%!
Now, that’s truly astonishing news. Caffeine, it turns out, acts as a catalyst inside the human body that boosts the beneficial effects of other substances. For example, according to the British newspaper, The Telegraph, in an article titled “The Surprising Health Benefits of Caffeine”:
“Combining a painkiller with caffeine could be the secret to curing your headache. Research from the University of Oxford Department of Clinical Neurosciences has shown that combining 200mg of ibuprofen with 100mg of caffeine is the most effective way of dealing with pain. So next time you have a headache, it might be worth serving that ibuprofen with a side order of an Americano.”
Most people have never even heard of glucuronolactone, so why did Targeted Nutrients make it the main ingredient in Wide Awake!?
This all-natural metabolite of glucose has actually been around in supplement form since the 1960’s when it was given to U.S. troops during the dark days of the Vietnam war as a natural means of uplifting mood and morale while relieving mental stress and depression.
Known as nature’s “nirvana compound,” glucoronolactone promotes brain energy, enhanced mental clarity and mild euphoria.
According to Brian D. Evans, author of How to Become Super Smart and Get Limitless Memory, glucuronolactone is a little-known “smart nutrient” that “works to fight fatigue and provide an overall sense of well-being.”
Jonathan Samson, M.D., Ph.D., says, “What’s known about glucuronolactone is that it allows an amazing natural energy increase, heightening both mood and mental clarity simultaneously.”
Both Energy-Enhancing and Mood-Boosting!
In other words, glucoronolactone is both ergogenic (i.e., performance, energy and stamina-enhancing) and euphoragenic (i.e., pleasure-inducing). It boosts brain energy and function and helps induce feelings of well-being or even mild euphoria by triggering your body’s “happy” brain chemicals.
The brain-boosting and mood-boosting benefits of glucoronolactone are so impressive, ex-Google employee Michael Brandt and Glassmap founder Geoffrey Woo, both Stanford graduates, admit to using it as part of their regular morning “nootropic brain stack” for achieving optimal brain function.
And glucoronolactone was even featured for its brain-boosting and mood-enhancing benefits on ABC TVs Shark Tank.
According to Health Monthly:
“Glucuronolactone delivers a valuable energy boost for the brain…giving you an extra edge to enhance your focus and concentration.”
And according to Nootriment.com:
“Glucoronolactone reduces sleepiness, increases focus, lightens the mood and quickens reaction times.”
Finally, according to NutriScience:
“Studies suggest that glucuronolactone…promotes mental performance and positive mood as well. When given glucuronolactone in a clinical study, subjects showed significant improvements in reaction time, concentration, and memory.”
As a bonus to the mood-boosting and energy-enhancing benefits of glucoronolactone, it’s also known to be one of the human body’s most important metabolites, being intimately involved in fatty acid synthesis, nucleotide synthesis, and amino acid synthesis – which could help explain some of its profoundly uplifting qualities on both mental and physical performance.
In other words, virtually all of your body’s metabolic building blocks are directly or indirectly aided by the presence of glucoronolactone, which means it’s needed for the very process of life, itself.
What’s more, glucoronolactone is completely natural. It’s made in the liver, out of glucose. And it can also be found in a variety of plant gums and other natural sources. It’s even found in wine, in small amounts.
Phenomenal Detoxifying Properties
As an added bonus, glucoronolactone turns out to be one of the body’s most important natural detoxifiers, being demonstrated in clinical trials to convert toxic substances into harmless water-soluble substances which can then be easily excreted through the kidneys rather than building up in the body.
Indeed, substances known to be detoxified from the body by glucoronolactone include:
- everyday pollutants, toxins, and carcinogens
- drugs like morphine and codeine
- harmful chemical substances such as hormone-disrupting xenoestrogens (that leach from plastic drinking bottles and that are found in shampoos as well as in pesticides used on foods)
In a nutshell, glucoronolactone is a powerful nutritional metabolite of glucose that boosts brain function, provides a profound sense of physical and mental well-being, increases stamina, improves metabolism, and helps detoxify the body – all at the same time.
And that’s why Targeted Nutrients chose to use glucoronolactone as the main nutrient ingredient in Wide Awake! when they formulated it.
There’s quite literally nothing else like glucoronolactone on the face of the earth. It’s an astonishingly effective all-natural energizer.
But it’s much more than that. It boosts and helps normalize the function of every bodily system, in a kind, gentle way. And it boosts the activity of your brain’s “feel good” chemicals. In short, it gives you bodily energy and makes you feel like a million bucks at the same time!
And as icing on the cake, glucoronolactone helps your body neutralize harmful toxins that could otherwise rob your body of energy and well-being and trigger the onset of illness.
Glucoronolactone + Caffeine = A Natural, Pleasure-Boosting Energizer!
And now you know exactly why Targeted Nutrients chose to combine the powerful brain-boosting, pleasure-inducing and healing benefits of glucuronolactone with a small nutritional dose (150 mg.) of caffeine in my energy-boosting supplement Wide Awake!
Used in moderation, caffeine is safe…healthful…boosts alertness, memory and recall…aids in recovery from physical exertion…helps protect against inflammation, chronic degenerative disease and many of the ravages of aging…and best yet, it makes other beneficial substances taken with it work even better than they would have worked without it.
It’s no wonder that caffeine is regularly consumed by a whopping ninety percent of the world’s population. And you’ve got to admit, it’s absolutely fascinating that mankind’s centuries-old use of caffeine, and experiential understanding of caffeine’s manifold health benefits, are finally being confirmed by modern science.
If you think the brain-boosting, pleasure-inducing and healing benefits of glucuronolactone sound good, just wait until you try it with a tiny bit of caffeine added. It will truly rock your world!
So if you’re sick and tired of guzzling down cup after cup of coffee each day just to stay alert and productive, then Wide Awake! is the safe, natural pleasure-boosting energizer you’ve been looking for all along.
Where to Find Wide Awake!
You found it! Targeted Nutrients is the only company in the world currently carrying Wide Awake!. And it’s gradually becoming one of our flagship supplements as more and more people learn about its astonishing, pleasure-inducing “pick-me-up” benefits.
So if you’re ready to quit slugging down coffee all day, or if you’re ready to quit using those over-priced, sugar-laden, health-robbing “energy drinks” to get through the afternoons, this is your chance to make the switch to safe, natural, health-enhancing, and unique caffeine and glucuronolactone formula, Wide Awake!, instead.
Since I’ve been using Wide Awake! my daily coffee consumption has practically dropped off the map. I love the taste of coffee. So I have to admit, I do have a cup from time to time. But I don’t need to. The profound feeling of alertness and (dare I say it?) mild pleasure I get from taking Wide Awake! each day is far better than coffee.
And unlike having to slug down cup after cup of coffee to get the caffeine I felt I needed to get through a demanding day, I only need to take Wide Awake!once a day. That’s it for me. And I sail through the day a smile on my face, a bounce in my step and profound mental clarity. I think you will too. Try it for yourself and experience the difference.
Learn how to try Targeted Nutrients’ high-quality Wide Awake! at a very special get-acquainted discount price, here.
Yours for better health the safe, natural way,
Steve Barwick, President